Serology and polymorphism of H-2L- locus encoded antigens

Chun Ming Huang, Huei Jen Su Huang, Jan Klein

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Thirty B10.W congenic lines were analysed serologically, both by direct cytotoxicity and by absorption, for the presence of H-2L antigens. Three new H-2L antigens, 73, 74, and 75, were discovered. The B10.W lines and the inbred strains can be classified into at least six H-2L phenogroups on the basis of their reactivity with H- 2dm2anti-H- 2d serum: BALB/c, B10.BUA1, B10.GAA37, B10.BUA16. B10.KPB128, and the negative group. Twenty-one D-end recom-binants were analysed for the possible separation of H-2D and H-2L loci. The failure to find such a separation indicates that the H-2D and H-2L loci are tightly linked. Serological analysis also indicated that the H- 2dm1 has lost most of its H-2L antigens but retained at least one specificity which can be detected by H- 2dm2 anti -H- 2d serum.

Original languageEnglish (US)
Pages (from-to)173-182
Number of pages10
JournalImmunogenetics
Volume9
Issue number1
DOIs
StatePublished - Dec 1979

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Serology
Antigens
Serum
H antigen

All Science Journal Classification (ASJC) codes

  • Immunology
  • Genetics

Cite this

Huang, C. M., Huang, H. J. S., & Klein, J. (1979). Serology and polymorphism of H-2L- locus encoded antigens. Immunogenetics, 9(1), 173-182. https://doi.org/10.1007/BF01570408
Huang, Chun Ming ; Huang, Huei Jen Su ; Klein, Jan. / Serology and polymorphism of H-2L- locus encoded antigens. In: Immunogenetics. 1979 ; Vol. 9, No. 1. pp. 173-182.
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Huang, CM, Huang, HJS & Klein, J 1979, 'Serology and polymorphism of H-2L- locus encoded antigens', Immunogenetics, vol. 9, no. 1, pp. 173-182. https://doi.org/10.1007/BF01570408

Serology and polymorphism of H-2L- locus encoded antigens. / Huang, Chun Ming; Huang, Huei Jen Su; Klein, Jan.

In: Immunogenetics, Vol. 9, No. 1, 12.1979, p. 173-182.

Research output: Contribution to journalArticle

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