Serotonin dysrégulation and psychopathology in anorexia nervosa and obsessive-compulsive disorder

Victoria Urrutia, Alice Morales, Mary V. Solanto

Research output: Contribution to journalArticle

9 Scopus citations


It has been hypothesized that anorexia nervosa is a subtype of obsessive-compulsive disorder (OCD). Serotonin dysrégulation may be the common mediator. This review evaluates the relevant literature, including psychopathology common to eating disorders and OCD; effects of anti-obsessive drugs in patients with eating disorders; serotonin’s role in eating behavior, impulse control, and anxiety; and effects of serotoninergic drugs in eating disorders and in OCD. The implications of these findings for a common etiology of anorexia nervosa and obsessive-compulsive disorder and for further neurobiological research with patients with eating disorders will also be discussed.

Original languageEnglish (US)
Pages (from-to)56-73
Number of pages18
JournalEating Disorders
Issue number1
Publication statusPublished - Jan 1 1995


All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

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