Serum gonadotropin, testosterone and prolactin concentrations throughout puberty in boys: A longitudinal study

Peter A. Lee, Robert B. Jaffe, A. Rees Midgley

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Forty-six boys were followed at 6- month intervals up to 48 months during the years of puberty with examinations to evaluate the extent of sexual development and with serum samplings to determine LH, FSH, testosterone and prolactin concentrations. LH levels rose throughout puberty, the initial rise of LH occurring before testosterone concentrations were significantly increased. Testosterone levels rose progressively from before the appearance of sexual hair until an adult distribution was achieved. Testosterone concentrations did not increase until after growth of the genitalia was appreciated while genital growth continued after elevations of testosterone were no longer detectable. Levels of FSH rose before sexual hair appeared but after the initial enlargement of the testes occurred. No further elevation of FSH occurred after midpuberty. Prolactin concentrations did not change throughout puberty.

Original languageEnglish (US)
Pages (from-to)664-672
Number of pages9
JournalJournal of Clinical Endocrinology and Metabolism
Volume39
Issue number4
DOIs
StatePublished - Oct 1974

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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