Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars

J. H. Herbein, R. J. Martin, Lester C. Griel, Jr., J. F. Kavanaugh

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Growth hormone (GH), insulin, cortisol, triiodothyronine (T3) and thyroxine (T4) were determined in serum of fetal pigs at 90, 100, 110 and 114 days of gestation and of newborn pigs at 1 and 24 hours of age. Fetal GH, T3 and cortisol increased between 90 and 110 days. GH concentration decreased between 110 and 114 days, while T3 and cortisol were unchanged. T4 was variable in fetal pigs and no relationship with T3 levels was apparent. Fetal insulin was constant at approximately 10 μU/ml. In newborn pigs there was a 3-fold and 2-fold increase in T3 and T4, respectively, during the first 24 hours of life. Cortisol in serum more than doubled during the first hour. Between 1 and 24 hours, there was a simultaneous decrease in cortisol and a 6-fold increase in insulin. No significant change in GH was noted during this time. Intraperitoneal insulin injected one hour before sacrifice induced a hypoglycemic response in newborn pigs, but not in fetal pigs.

Original languageEnglish (US)
Pages (from-to)277-283
Number of pages7
JournalGrowth
Volume41
Issue number4
StatePublished - Dec 1 1977

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Blood Glucose
Swine
Hydrocortisone
Hormones
Insulin
Growth Hormone
Serum
Triiodothyronine
Fetal Development
Thyroxine
Hypoglycemic Agents
Pregnancy

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

Cite this

Herbein, J. H., Martin, R. J., Griel, Jr., L. C., & Kavanaugh, J. F. (1977). Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars. Growth, 41(4), 277-283.
Herbein, J. H. ; Martin, R. J. ; Griel, Jr., Lester C. ; Kavanaugh, J. F. / Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars. In: Growth. 1977 ; Vol. 41, No. 4. pp. 277-283.
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Herbein, JH, Martin, RJ, Griel, Jr., LC & Kavanaugh, JF 1977, 'Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars', Growth, vol. 41, no. 4, pp. 277-283.

Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars. / Herbein, J. H.; Martin, R. J.; Griel, Jr., Lester C.; Kavanaugh, J. F.

In: Growth, Vol. 41, No. 4, 01.12.1977, p. 277-283.

Research output: Contribution to journalArticle

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Herbein JH, Martin RJ, Griel, Jr. LC, Kavanaugh JF. Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars. Growth. 1977 Dec 1;41(4):277-283.