Simultaneous classification and feature clustering using discriminant vector quantization with applications to microarray data analysis

Jia Li, Hongyuan Zha

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations

Abstract

In many applications of supervised learning, automatic feature clustering is often desirable for a better understanding of the interaction among the various features as well as the interplay between the features and the class labels. In addition, for high dimensional data sets, feature clustering has the potential for improvement in classification accuracy and reduction in computational complexity. In this paper, a method is developed for simultaneous classification and feature clustering by extending discriminant vector quantization (DVQ), a prototype classification method derived from the principle of minimum description length using source coding techniques. The method incorporates feature clustering with classification performed by fusing features in the same clusters. To illustrate its effectiveness, the method has been applied to microarray gene expression data for human lymphoma classification. It is demonstrated that incorporating feature clustering improves classification accuracy, and the clusters generated match well with biological meaningful gene expression signature groups.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Computer Society Bioinformatics Conference, CSB 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages246-255
Number of pages10
ISBN (Electronic)076951653X, 9780769516530
DOIs
StatePublished - Jan 1 2002
Event1st International IEEE Computer Society Bioinformatics Conference, CSB 2002 - Stanford, United States
Duration: Aug 14 2002Aug 16 2002

Publication series

NameProceedings - IEEE Computer Society Bioinformatics Conference, CSB 2002

Other

Other1st International IEEE Computer Society Bioinformatics Conference, CSB 2002
CountryUnited States
CityStanford
Period8/14/028/16/02

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All Science Journal Classification (ASJC) codes

  • Artificial Intelligence
  • Software
  • Biomedical Engineering
  • Health Informatics

Cite this

Li, J., & Zha, H. (2002). Simultaneous classification and feature clustering using discriminant vector quantization with applications to microarray data analysis. In Proceedings - IEEE Computer Society Bioinformatics Conference, CSB 2002 (pp. 246-255). [1039347] (Proceedings - IEEE Computer Society Bioinformatics Conference, CSB 2002). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CSB.2002.1039347