Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification

Tian Tian, Heng Xiao, Xiaolian Zhang, Shuang Peng, Xiaoe Zhang, Shan Guo, Shaoru Wang, Songmei Liu, Xin Zhou, Craig Meyers, Xiang Zhou

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.

Original languageEnglish (US)
Pages (from-to)75-77
Number of pages3
JournalChemical Communications
Volume49
Issue number1
DOIs
StatePublished - Jan 4 2013

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MicroRNAs
Amplification
Fluorescence

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Tian, Tian ; Xiao, Heng ; Zhang, Xiaolian ; Peng, Shuang ; Zhang, Xiaoe ; Guo, Shan ; Wang, Shaoru ; Liu, Songmei ; Zhou, Xin ; Meyers, Craig ; Zhou, Xiang. / Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification. In: Chemical Communications. 2013 ; Vol. 49, No. 1. pp. 75-77.
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Tian, T, Xiao, H, Zhang, X, Peng, S, Zhang, X, Guo, S, Wang, S, Liu, S, Zhou, X, Meyers, C & Zhou, X 2013, 'Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification', Chemical Communications, vol. 49, no. 1, pp. 75-77. https://doi.org/10.1039/c2cc36728a

Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification. / Tian, Tian; Xiao, Heng; Zhang, Xiaolian; Peng, Shuang; Zhang, Xiaoe; Guo, Shan; Wang, Shaoru; Liu, Songmei; Zhou, Xin; Meyers, Craig; Zhou, Xiang.

In: Chemical Communications, Vol. 49, No. 1, 04.01.2013, p. 75-77.

Research output: Contribution to journalArticle

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AU - Tian, Tian

AU - Xiao, Heng

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AU - Peng, Shuang

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AU - Guo, Shan

AU - Wang, Shaoru

AU - Liu, Songmei

AU - Zhou, Xin

AU - Meyers, Craig

AU - Zhou, Xiang

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