Sinonasal teratocarcinosarcoma

Yan Ye Su, Michael Friedman, Chun Chen Huang, Meghan N. Wilson, Hsin Ching Lin

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Sinonasal teratocarcinosarcoma (SNTCS) is a rare and aggressive neoplasm characterized by the combination of malignant teratoma and carcinosarcoma. Sinonasal teratocarcinosarcoma usually is found mainly among adults, and the common original sites of SNTCS were nasal cavities and paranasal sinuses. There are fewer than 50 reported SNTCS cases in the literature. The most common cause of treatment failure is local recurrence. Distant metastasis of SNTCS is seldom described because of the invasive character of the cancer. We report on a 52-year-old man with SNTCS involving the left sinonasal cavity. Recurrent cervical metastasis developed in the 18th, 23rd, and 28th month after initial sinonasal surgery. Despite multiple aggressive neck surgeries and postoperative adjuvant radiotherapy, the patient died of lung metastasis 43 months after the initial surgery. Our patient was younger than other reported patients with SNTCS; besides, good locoregional control and lung metastasis have not been reported previously. An aggressive elective neck dissection should be performed in the early disease stage, and more attention should be given to the soft tissue surrounding any possible lymphadenopathy. This may decrease the risk of lower cervical lymph node or distant metastasis in patients with SNTCS. Crown

Original languageEnglish (US)
Pages (from-to)300-303
Number of pages4
JournalAmerican Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume31
Issue number4
DOIs
StatePublished - Jul 1 2010

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Neoplasm Metastasis
Paranasal Sinuses
Carcinosarcoma
Lung
Adjuvant Radiotherapy
Neck Dissection
Malignant Teratocarcinosarcoma
Nasal Cavity
Teratoma
Treatment Failure
Crowns
Neoplasms
Neck
Lymph Nodes
Recurrence

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Su, Yan Ye ; Friedman, Michael ; Huang, Chun Chen ; Wilson, Meghan N. ; Lin, Hsin Ching. / Sinonasal teratocarcinosarcoma. In: American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 2010 ; Vol. 31, No. 4. pp. 300-303.
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Sinonasal teratocarcinosarcoma. / Su, Yan Ye; Friedman, Michael; Huang, Chun Chen; Wilson, Meghan N.; Lin, Hsin Ching.

In: American Journal of Otolaryngology - Head and Neck Medicine and Surgery, Vol. 31, No. 4, 01.07.2010, p. 300-303.

Research output: Contribution to journalArticle

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AU - Huang, Chun Chen

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