SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

Jeremy Hengst; Taryn E. Dick; Arati Sharma; Kenichiro Doi; Shailaja Hegde; Su Fern Tan; Laura Geffert; Todd E. Fox; Arun K. Sharma; Dhimant Desai; Shantu Amin; Mark Kester; Thomas P. Loughran; Robert Paulson; David Claxton; Hong-Gang Wang; Jong Yun

SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

Jeremy Hengst, Taryn E. Dick, Arati Sharma, Kenichiro Doi, Shailaja Hegde, Su Fern Tan, Laura Geffert, Todd E. Fox, Arun K. Sharma, Dhimant Desai, Shantu Amin, Mark Kester, Thomas P. Loughran, Robert Paulson, David Claxton, Hong-Gang Wang, Jong Yun

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	109-121
Journal	Cancer Translational Medicine
Volume	3
Issue number	4
State	Published - 2017

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http://www.cancertm.com/article.asp?issn=2395-3977;year=2017;volume=3;issue=4;spage=109;epage=121;aulast=Hengst;type=0

Cite this

Hengst, J., Dick, T. E., Sharma, A., Doi, K., Hegde, S., Tan, S. F., Geffert, L., Fox, T. E., Sharma, A. K., Desai, D., Amin, S., Kester, M., Loughran, T. P., Paulson, R., Claxton, D., Wang, H-G., & Yun, J. (2017). SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models. Cancer Translational Medicine, 3(4), 109-121. http://www.cancertm.com/article.asp?issn=2395-3977;year=2017;volume=3;issue=4;spage=109;epage=121;aulast=Hengst;type=0

Hengst, Jeremy ; Dick, Taryn E. ; Sharma, Arati ; Doi, Kenichiro ; Hegde, Shailaja ; Tan, Su Fern ; Geffert, Laura ; Fox, Todd E. ; Sharma, Arun K. ; Desai, Dhimant ; Amin, Shantu ; Kester, Mark ; Loughran, Thomas P. ; Paulson, Robert ; Claxton, David ; Wang, Hong-Gang ; Yun, Jong. / SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models. In: Cancer Translational Medicine. 2017 ; Vol. 3, No. 4. pp. 109-121.

@article{ec104b57306b474f8f6e537039de6332,

title = "SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models",

author = "Jeremy Hengst and Dick, {Taryn E.} and Arati Sharma and Kenichiro Doi and Shailaja Hegde and Tan, {Su Fern} and Laura Geffert and Fox, {Todd E.} and Sharma, {Arun K.} and Dhimant Desai and Shantu Amin and Mark Kester and Loughran, {Thomas P.} and Robert Paulson and David Claxton and Hong-Gang Wang and Jong Yun",

year = "2017",

language = "English (US)",

volume = "3",

pages = "109--121",

journal = "Cancer Translational Medicine",

issn = "2395-3012",

number = "4",

}

Hengst, J, Dick, TE, Sharma, A, Doi, K, Hegde, S, Tan, SF, Geffert, L, Fox, TE, Sharma, AK , Desai, D , Amin, S, Kester, M, Loughran, TP, Paulson, R , Claxton, D , Wang, H-G & Yun, J 2017, 'SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models', Cancer Translational Medicine, vol. 3, no. 4, pp. 109-121. <http://www.cancertm.com/article.asp?issn=2395-3977;year=2017;volume=3;issue=4;spage=109;epage=121;aulast=Hengst;type=0>

SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models. / Hengst, Jeremy; Dick, Taryn E.; Sharma, Arati; Doi, Kenichiro; Hegde, Shailaja; Tan, Su Fern; Geffert, Laura; Fox, Todd E.; Sharma, Arun K.; Desai, Dhimant ; Amin, Shantu; Kester, Mark; Loughran, Thomas P.; Paulson, Robert ; Claxton, David ; Wang, Hong-Gang ; Yun, Jong.

In: Cancer Translational Medicine, Vol. 3, No. 4, 2017, p. 109-121.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

AU - Hengst, Jeremy

AU - Dick, Taryn E.

AU - Sharma, Arati

AU - Doi, Kenichiro

AU - Hegde, Shailaja

AU - Tan, Su Fern

AU - Geffert, Laura

AU - Fox, Todd E.

AU - Sharma, Arun K.

AU - Desai, Dhimant

AU - Amin, Shantu

AU - Kester, Mark

AU - Loughran, Thomas P.

AU - Paulson, Robert

AU - Claxton, David

AU - Wang, Hong-Gang

AU - Yun, Jong

PY - 2017

Y1 - 2017

M3 - Article

VL - 3

SP - 109

EP - 121

JO - Cancer Translational Medicine

JF - Cancer Translational Medicine

SN - 2395-3012

IS - 4

ER -