Sleep Apnea and its Association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity

Georgia Trakada, George P. Chrousos, Slobodanka Pejovic, Alexandros N. Vgontzas

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive collapse of the upper airway during sleep leading to significant hypoxemia and recurrent arousals from sleep. OSA is associated with considerable morbidity and mortality. Four percent of adult men and two percent of adult women in general population random samples meet the current clinical and polysomnographic criteria for the diagnosis of sleep apnea. Obesity is the most important reversible risk factor for OSA. In this article, the authors review knowledge accumulated during the last 10 years about sleep apnea and its association with the stress system, inflammation, insulin resistance and visceral obesity.

Original languageEnglish (US)
Pages (from-to)251-261
Number of pages11
JournalSleep Medicine Clinics
Volume2
Issue number2
DOIs
StatePublished - Jun 2007

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

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