Slowed information processing in HIV-1 disease

Antolin Llorente, Eric N. Miller, Louis F. D'Elia, Ola A. Selnes, Jerry Wesch, James T. Becker, Paul Satz

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

This investigation examined the effects of HIV-1 infection on speeded complex cognitive processing in a group of HIV-negative (n = 666), HIV- positive symptomatic (n = 156), and HIV-positive asymptomatic (n = 623) participants while controlling for the effects of slowed motor functioning, peripheral neuropathy, and several other putative confounds. Stroop Interference and reaction-time tasks served as anchor procedures to assess cognitive processing. The present findings suggest that HIV-1 infection is capable of compromising CNS-mediated cognitive processes (speeded processing) infringing upon their efficacy in the symptomatic stages of the disease while sparing individuals in the asymptomatic stage. The detrimental effects observed on information-processing mechanisms associated with HIV infection persisted despite the use of procedures to control for peripheral nerve integrity and other potential confounds.

Original languageEnglish (US)
Pages (from-to)60-72
Number of pages13
JournalJournal of Clinical and Experimental Neuropsychology
Volume20
Issue number1
DOIs
StatePublished - Jul 20 1998

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Automatic Data Processing
HIV Infections
HIV-1
HIV
Peripheral Nervous System Diseases
Peripheral Nerves

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Neurology
  • Clinical Neurology

Cite this

Llorente, A., Miller, E. N., D'Elia, L. F., Selnes, O. A., Wesch, J., Becker, J. T., & Satz, P. (1998). Slowed information processing in HIV-1 disease. Journal of Clinical and Experimental Neuropsychology, 20(1), 60-72. https://doi.org/10.1076/jcen.20.1.60.1489
Llorente, Antolin ; Miller, Eric N. ; D'Elia, Louis F. ; Selnes, Ola A. ; Wesch, Jerry ; Becker, James T. ; Satz, Paul. / Slowed information processing in HIV-1 disease. In: Journal of Clinical and Experimental Neuropsychology. 1998 ; Vol. 20, No. 1. pp. 60-72.
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Llorente, A, Miller, EN, D'Elia, LF, Selnes, OA, Wesch, J, Becker, JT & Satz, P 1998, 'Slowed information processing in HIV-1 disease', Journal of Clinical and Experimental Neuropsychology, vol. 20, no. 1, pp. 60-72. https://doi.org/10.1076/jcen.20.1.60.1489

Slowed information processing in HIV-1 disease. / Llorente, Antolin; Miller, Eric N.; D'Elia, Louis F.; Selnes, Ola A.; Wesch, Jerry; Becker, James T.; Satz, Paul.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 20, No. 1, 20.07.1998, p. 60-72.

Research output: Contribution to journalArticle

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