SMART coils for intracranial aneurysm embolization: Initial outcomes

Adeel Ilyas, Thomas J. Buell, Ching Jen Chen, Dale Ding, Daniel M.S. Raper, Davis G. Taylor, Jennifer D. Sokolowski, Kenneth Liu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives Endovascular technology for the treatment of intracranial aneurysms continues to rapidly evolve. The SMART coil (Penumbra Inc., Alameda, CA, USA) is a novel microcoil designed to enhance deliverability. The aim of this single-center, retrospective cohort study is to assess the initial outcomes after aneurysm embolization using SMART coils. Patients and methods We reviewed consecutive patients with intracranial aneurysms who underwent endovascular embolization using SMART coils from June 2016 to January 2017. Baseline and initial outcomes data were analyzed. Results The study cohort was comprised of 32 patients with 33 aneurysms. The mean age was 55.8 years. The majority (85%) of aneurysms were located in the anterior circulation. The mean aneurysm maximum diameter and neck width were 6.0 mm and 3.1 mm, respectively. Dome irregularity and fusiform aneurysm morphology were noted in 33% and 9% of aneurysms, respectively, and 15% presented with subarachnoid hemorrhage. No serious procedural complications occurred, including microcatheter prolapse, intraprocedural aneurysm rupture, or thromboembolism. Device malfunction occurred in one case (3%). The mean packing density was 25%, and the degree of immediate post-embolization aneurysm occlusion was a modified Raymond-Roy grade I, II, IIIa, and IIIb in 48%, 27%, 18%, and 6%, respectively. Conclusion Our preliminary findings suggest that the SMART coil has a favorable initial risk to benefit profile for the embolization of appropriately selected aneurysms. Additional studies of larger cohorts are necessary to determine the mid-term and long-term clinical and angiographic outcomes of aneurysm patients treated with the SMART coil.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalClinical Neurology and Neurosurgery
Volume164
DOIs
StatePublished - Jan 1 2018

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Intracranial Aneurysm
Aneurysm
Cohort Studies
Prolapse
Thromboembolism
Subarachnoid Hemorrhage
Rupture
Neck
Retrospective Studies
Technology
Equipment and Supplies

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Ilyas, A., Buell, T. J., Chen, C. J., Ding, D., Raper, D. M. S., Taylor, D. G., ... Liu, K. (2018). SMART coils for intracranial aneurysm embolization: Initial outcomes. Clinical Neurology and Neurosurgery, 164, 87-91. https://doi.org/10.1016/j.clineuro.2017.11.020
Ilyas, Adeel ; Buell, Thomas J. ; Chen, Ching Jen ; Ding, Dale ; Raper, Daniel M.S. ; Taylor, Davis G. ; Sokolowski, Jennifer D. ; Liu, Kenneth. / SMART coils for intracranial aneurysm embolization : Initial outcomes. In: Clinical Neurology and Neurosurgery. 2018 ; Vol. 164. pp. 87-91.
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title = "SMART coils for intracranial aneurysm embolization: Initial outcomes",
abstract = "Objectives Endovascular technology for the treatment of intracranial aneurysms continues to rapidly evolve. The SMART coil (Penumbra Inc., Alameda, CA, USA) is a novel microcoil designed to enhance deliverability. The aim of this single-center, retrospective cohort study is to assess the initial outcomes after aneurysm embolization using SMART coils. Patients and methods We reviewed consecutive patients with intracranial aneurysms who underwent endovascular embolization using SMART coils from June 2016 to January 2017. Baseline and initial outcomes data were analyzed. Results The study cohort was comprised of 32 patients with 33 aneurysms. The mean age was 55.8 years. The majority (85{\%}) of aneurysms were located in the anterior circulation. The mean aneurysm maximum diameter and neck width were 6.0 mm and 3.1 mm, respectively. Dome irregularity and fusiform aneurysm morphology were noted in 33{\%} and 9{\%} of aneurysms, respectively, and 15{\%} presented with subarachnoid hemorrhage. No serious procedural complications occurred, including microcatheter prolapse, intraprocedural aneurysm rupture, or thromboembolism. Device malfunction occurred in one case (3{\%}). The mean packing density was 25{\%}, and the degree of immediate post-embolization aneurysm occlusion was a modified Raymond-Roy grade I, II, IIIa, and IIIb in 48{\%}, 27{\%}, 18{\%}, and 6{\%}, respectively. Conclusion Our preliminary findings suggest that the SMART coil has a favorable initial risk to benefit profile for the embolization of appropriately selected aneurysms. Additional studies of larger cohorts are necessary to determine the mid-term and long-term clinical and angiographic outcomes of aneurysm patients treated with the SMART coil.",
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Ilyas, A, Buell, TJ, Chen, CJ, Ding, D, Raper, DMS, Taylor, DG, Sokolowski, JD & Liu, K 2018, 'SMART coils for intracranial aneurysm embolization: Initial outcomes', Clinical Neurology and Neurosurgery, vol. 164, pp. 87-91. https://doi.org/10.1016/j.clineuro.2017.11.020

SMART coils for intracranial aneurysm embolization : Initial outcomes. / Ilyas, Adeel; Buell, Thomas J.; Chen, Ching Jen; Ding, Dale; Raper, Daniel M.S.; Taylor, Davis G.; Sokolowski, Jennifer D.; Liu, Kenneth.

In: Clinical Neurology and Neurosurgery, Vol. 164, 01.01.2018, p. 87-91.

Research output: Contribution to journalArticle

TY - JOUR

T1 - SMART coils for intracranial aneurysm embolization

T2 - Initial outcomes

AU - Ilyas, Adeel

AU - Buell, Thomas J.

AU - Chen, Ching Jen

AU - Ding, Dale

AU - Raper, Daniel M.S.

AU - Taylor, Davis G.

AU - Sokolowski, Jennifer D.

AU - Liu, Kenneth

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Objectives Endovascular technology for the treatment of intracranial aneurysms continues to rapidly evolve. The SMART coil (Penumbra Inc., Alameda, CA, USA) is a novel microcoil designed to enhance deliverability. The aim of this single-center, retrospective cohort study is to assess the initial outcomes after aneurysm embolization using SMART coils. Patients and methods We reviewed consecutive patients with intracranial aneurysms who underwent endovascular embolization using SMART coils from June 2016 to January 2017. Baseline and initial outcomes data were analyzed. Results The study cohort was comprised of 32 patients with 33 aneurysms. The mean age was 55.8 years. The majority (85%) of aneurysms were located in the anterior circulation. The mean aneurysm maximum diameter and neck width were 6.0 mm and 3.1 mm, respectively. Dome irregularity and fusiform aneurysm morphology were noted in 33% and 9% of aneurysms, respectively, and 15% presented with subarachnoid hemorrhage. No serious procedural complications occurred, including microcatheter prolapse, intraprocedural aneurysm rupture, or thromboembolism. Device malfunction occurred in one case (3%). The mean packing density was 25%, and the degree of immediate post-embolization aneurysm occlusion was a modified Raymond-Roy grade I, II, IIIa, and IIIb in 48%, 27%, 18%, and 6%, respectively. Conclusion Our preliminary findings suggest that the SMART coil has a favorable initial risk to benefit profile for the embolization of appropriately selected aneurysms. Additional studies of larger cohorts are necessary to determine the mid-term and long-term clinical and angiographic outcomes of aneurysm patients treated with the SMART coil.

AB - Objectives Endovascular technology for the treatment of intracranial aneurysms continues to rapidly evolve. The SMART coil (Penumbra Inc., Alameda, CA, USA) is a novel microcoil designed to enhance deliverability. The aim of this single-center, retrospective cohort study is to assess the initial outcomes after aneurysm embolization using SMART coils. Patients and methods We reviewed consecutive patients with intracranial aneurysms who underwent endovascular embolization using SMART coils from June 2016 to January 2017. Baseline and initial outcomes data were analyzed. Results The study cohort was comprised of 32 patients with 33 aneurysms. The mean age was 55.8 years. The majority (85%) of aneurysms were located in the anterior circulation. The mean aneurysm maximum diameter and neck width were 6.0 mm and 3.1 mm, respectively. Dome irregularity and fusiform aneurysm morphology were noted in 33% and 9% of aneurysms, respectively, and 15% presented with subarachnoid hemorrhage. No serious procedural complications occurred, including microcatheter prolapse, intraprocedural aneurysm rupture, or thromboembolism. Device malfunction occurred in one case (3%). The mean packing density was 25%, and the degree of immediate post-embolization aneurysm occlusion was a modified Raymond-Roy grade I, II, IIIa, and IIIb in 48%, 27%, 18%, and 6%, respectively. Conclusion Our preliminary findings suggest that the SMART coil has a favorable initial risk to benefit profile for the embolization of appropriately selected aneurysms. Additional studies of larger cohorts are necessary to determine the mid-term and long-term clinical and angiographic outcomes of aneurysm patients treated with the SMART coil.

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