Smartphone based optical spectrometer for diffusive reflectance spectroscopic measurement of hemoglobin

Perry Edwards, Chenji Zhang, Baigang Zhang, Xiangqian Hong, Vivek K. Nagarajan, Bing Yu, Zhiwen Liu

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a resolution of ∼5 nm in a wavelength range from 400 nm to 1000 nm. We further developed a diffuse reflectance spectroscopy system using the smartphone spectrometer and demonstrated the capability of hemoglobin measurement. Proof of concept studies of tissue phantoms yielded a mean error of 9.2% on hemoglobin concentration measurement, comparable to that obtained with a commercial benchtop spectrometer. The smartphone G-Fresnel spectrometer and the diffuse reflectance spectroscopy system can potentially enable new point-of-care opportunities, such as cancer screening.

Original languageEnglish (US)
Article number12224
JournalScientific reports
Volume7
Issue number1
DOIs
StatePublished - Dec 1 2017

All Science Journal Classification (ASJC) codes

  • General

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