Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant Solenopsis invicta

Fabio Manfredini, Oksana Riba-Grognuz, Yannick Wurm, Laurent Keller, De Wayne Shoemaker, Christina M. Grozinger

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

One of the fundamental questions in biology is how cooperative and altruistic behaviors evolved. The majority of studies seeking to identify the genes regulating these behaviors have been performed in systems where behavioral and physiological differences are relatively fixed, such as in the honey bee. During colony founding in the monogyne (one queen per colony) social form of the fire ant Solenopsis invicta, newly-mated queens may start new colonies either individually (haplometrosis) or in groups (pleometrosis). However, only one queen (the "winner") in pleometrotic associations survives and takes the lead of the young colony while the others (the "losers") are executed. Thus, colony founding in fire ants provides an excellent system in which to examine the genes underpinning cooperative behavior and how the social environment shapes the expression of these genes. We developed a new whole genome microarray platform for S. invicta to characterize the gene expression patterns associated with colony founding behavior. First, we compared haplometrotic queens, pleometrotic winners and pleometrotic losers. Second, we manipulated pleometrotic couples in order to switch or maintain the social ranks of the two cofoundresses. Haplometrotic and pleometrotic queens differed in the expression of genes involved in stress response, aging, immunity, reproduction and lipid biosynthesis. Smaller sets of genes were differentially expressed between winners and losers. In the second experiment, switching social rank had a much greater impact on gene expression patterns than the initial/final rank. Expression differences for several candidate genes involved in key biological processes were confirmed using qRT-PCR. Our findings indicate that, in S. invicta, social environment plays a major role in the determination of the patterns of gene expression, while the queen's physiological state is secondary. These results highlight the powerful influence of social environment on regulation of the genomic state, physiology and ultimately, social behavior of animals.

Original languageEnglish (US)
Article numbere1003633
JournalPLoS genetics
Volume9
Issue number8
DOIs
StatePublished - Aug 1 2013

Fingerprint

colony founding
fire ants
Solenopsis invicta
Ants
queen insects
ant
Social Environment
Gene Expression
social environment
gene
gene expression
Genes
Cooperative Behavior
cooperatives
Biological Phenomena
genes
Honey
Social Behavior
cooperative behavior
Bees

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Genetics(clinical)
  • Cancer Research

Cite this

Manfredini, Fabio ; Riba-Grognuz, Oksana ; Wurm, Yannick ; Keller, Laurent ; Shoemaker, De Wayne ; Grozinger, Christina M. / Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant Solenopsis invicta. In: PLoS genetics. 2013 ; Vol. 9, No. 8.
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Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant Solenopsis invicta. / Manfredini, Fabio; Riba-Grognuz, Oksana; Wurm, Yannick; Keller, Laurent; Shoemaker, De Wayne; Grozinger, Christina M.

In: PLoS genetics, Vol. 9, No. 8, e1003633, 01.08.2013.

Research output: Contribution to journalArticle

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