Solid phase deprotection of 2-nitrobenzenesulfonamides: Synthesis of simple 2-(alkylamino)-pyrroles

Michael De Rosa, Nicola Stepani, Todd Cole, Jaclyn Fried, Lisa Huang-Pang, Lori Peacock, Michael Pro

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The 2-nitrobenzenesulfonamide cleavage using a solid-phase thiophenolate reagent gives simple 2-(alkylamino)-pyrroles without the presence of the competing nucleophilic substitution product.

Original languageEnglish (US)
Pages (from-to)5715-5717
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number34
DOIs
StatePublished - Aug 22 2005

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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