Cocrystals are multicomponent solids with organic molecules assembled in combination to form a crystalline solid with properties different than the individual components. A cocrystal typically consists of a target molecule crystallized with a second molecule, or cocrystal former, employed to influence properties of the target (e.g. solubility). The conformer interacts with the target via intermolecular forces (e.g. hydrogen bonds) that hold the components together. The modularity of a cocrystal makes such solids attractive for applications where fine-tuning of properties is important (e.g. optical). In this presentation, we describe the use of sonochemistry to form cocrystals of nanoscale dimensions. In contrast to single-component solids, cocrystals present a fundamentally different challenge with respect to those reprecipitation methods used to form nanocrystals since the components of a cocrystal will tend to exhibit different solubilities. We show that sonochemistry affords nano-cocrystals with properties (e.g. reactivity) that contrast solids of macroscale dimensions. Related applications of sonochemistry to afford singlecomponent nanocrystals will also be presented.
|Original language||English (US)|
|Journal||Proceedings of Meetings on Acoustics|
|State||Published - Jun 19 2013|
|Event||21st International Congress on Acoustics, ICA 2013 - 165th Meeting of the Acoustical Society of America - Montreal, QC, Canada|
Duration: Jun 2 2013 → Jun 7 2013
All Science Journal Classification (ASJC) codes
- Acoustics and Ultrasonics