Soy-polysaccharide fiber

Effect on diarrhea in tube-fed, head-injured patients

David Frankenfield, P. L. Beyer

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

In a randomized, double-blind, crossover study the effect of tube-feeding with soy-polysaccharide fiber (SPF) vs without SPF on stool weight (SW), stool consistency (SC), fecal nitrogen (FN), and incidence of diarrhea (ID) was compared in nine head-injured subjects; associations with feeding volume, albumin level, and medications were also examined. Subjects with and without SPF had (χ̄ ± SEM) of 245 ± 47 and 277 ± 49 g/d, SC of 2.17 ± 0.01 and 2.52 ± 0.13 (3 is watery) (p < 0.01), FN of 1.35 ± 0.45 and 1.36 ± 0.33 g/d, and ID of 33% and 44%, respectively. Significant treatment x treatment-sequence interaction nullified results for SW and SC. Neither FN nor ID were affected by SPF. The condition of all variables tended to improve over time. Certain medications and SPF were predictive of SW and SC; albumin and tube-feeding volume were not. SPF-containing tube feedings did not seem to have an effect on bowel function in these well-nourished head-injured patients.

Original languageEnglish (US)
JournalAmerican Journal of Clinical Nutrition
Volume50
Issue number3
DOIs
StatePublished - Jan 1 1989

Fingerprint

Polysaccharides
Diarrhea
Head
Enteral Nutrition
Nitrogen
Weights and Measures
Albumins
Incidence
Double-Blind Method
Cross-Over Studies
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

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abstract = "In a randomized, double-blind, crossover study the effect of tube-feeding with soy-polysaccharide fiber (SPF) vs without SPF on stool weight (SW), stool consistency (SC), fecal nitrogen (FN), and incidence of diarrhea (ID) was compared in nine head-injured subjects; associations with feeding volume, albumin level, and medications were also examined. Subjects with and without SPF had (χ̄ ± SEM) of 245 ± 47 and 277 ± 49 g/d, SC of 2.17 ± 0.01 and 2.52 ± 0.13 (3 is watery) (p < 0.01), FN of 1.35 ± 0.45 and 1.36 ± 0.33 g/d, and ID of 33{\%} and 44{\%}, respectively. Significant treatment x treatment-sequence interaction nullified results for SW and SC. Neither FN nor ID were affected by SPF. The condition of all variables tended to improve over time. Certain medications and SPF were predictive of SW and SC; albumin and tube-feeding volume were not. SPF-containing tube feedings did not seem to have an effect on bowel function in these well-nourished head-injured patients.",
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Soy-polysaccharide fiber : Effect on diarrhea in tube-fed, head-injured patients. / Frankenfield, David; Beyer, P. L.

In: American Journal of Clinical Nutrition, Vol. 50, No. 3, 01.01.1989.

Research output: Contribution to journalArticle

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