TY - JOUR
T1 - Soy-polysaccharide fiber
T2 - Effect on diarrhea in tube-fed, head-injured patients
AU - Frankenfield, David
AU - Beyer, P. L.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - In a randomized, double-blind, crossover study the effect of tube-feeding with soy-polysaccharide fiber (SPF) vs without SPF on stool weight (SW), stool consistency (SC), fecal nitrogen (FN), and incidence of diarrhea (ID) was compared in nine head-injured subjects; associations with feeding volume, albumin level, and medications were also examined. Subjects with and without SPF had (χ̄ ± SEM) of 245 ± 47 and 277 ± 49 g/d, SC of 2.17 ± 0.01 and 2.52 ± 0.13 (3 is watery) (p < 0.01), FN of 1.35 ± 0.45 and 1.36 ± 0.33 g/d, and ID of 33% and 44%, respectively. Significant treatment x treatment-sequence interaction nullified results for SW and SC. Neither FN nor ID were affected by SPF. The condition of all variables tended to improve over time. Certain medications and SPF were predictive of SW and SC; albumin and tube-feeding volume were not. SPF-containing tube feedings did not seem to have an effect on bowel function in these well-nourished head-injured patients.
AB - In a randomized, double-blind, crossover study the effect of tube-feeding with soy-polysaccharide fiber (SPF) vs without SPF on stool weight (SW), stool consistency (SC), fecal nitrogen (FN), and incidence of diarrhea (ID) was compared in nine head-injured subjects; associations with feeding volume, albumin level, and medications were also examined. Subjects with and without SPF had (χ̄ ± SEM) of 245 ± 47 and 277 ± 49 g/d, SC of 2.17 ± 0.01 and 2.52 ± 0.13 (3 is watery) (p < 0.01), FN of 1.35 ± 0.45 and 1.36 ± 0.33 g/d, and ID of 33% and 44%, respectively. Significant treatment x treatment-sequence interaction nullified results for SW and SC. Neither FN nor ID were affected by SPF. The condition of all variables tended to improve over time. Certain medications and SPF were predictive of SW and SC; albumin and tube-feeding volume were not. SPF-containing tube feedings did not seem to have an effect on bowel function in these well-nourished head-injured patients.
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U2 - 10.1093/ajcn/50.3.533
DO - 10.1093/ajcn/50.3.533
M3 - Article
C2 - 2549780
AN - SCOPUS:0024441503
VL - 50
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
SN - 0002-9165
IS - 3
ER -