Spatially varying porosity with continuous path plan for hollowed tissue scaffolds

A. K.M.B. Khoda, I. T. Ozbolat, B. Koc

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, a bio-inspired scaffold design has been proposed by incorporating its functional (biological requirement) and fabrication constraint into the design processes. The proposed new methodology generates functionally gradient porosity along the hollowed scaffold architecture with desired level of control by combining two geometrically oriented consecutive layers. The resulting set of layers address the repeatable, interconnected and controllable pores. Modeling of the first layer starts with discretizing internal region by connecting ruling lines between internal and external features using a dynamic programming algorithm. These feature connecting ruling lines act as resolution for the proposed method. Then by accumulating those ruling lines, the region has been divided into equal area sub-regions. In the second layer, the desired pore size and hence the porosity has been achieved by geometrically partitioning those sub-regions. And thus the combined set of layers achieves the desired controlled variational porosity along the scaffold architecture.To ensure a continuous and interconnected tool path, optimized zigzag pattern followed by a concentric spiral like optimal layers are generated based on the required biological and mechanical properties. Several examples will be presented to demonstrate the proposed methodology. The designed examples will also be fabricated layer-by-layer using a micro-nozzle biomaterial deposition system.

Original languageEnglish (US)
Title of host publicationInnovative Developments in Virtual and Physical Prototyping - Proceedings of the 5th International Conference on Advanced Research and Rapid Prototyping
Pages73-77
Number of pages5
StatePublished - 2012
Event5th International Conference on Advanced Research in Virtual and Physical Prototyping, VR@P 2011 - Leiria, Portugal
Duration: Sep 28 2011Oct 1 2011

Publication series

NameInnovative Developments in Virtual and Physical Prototyping - Proceedings of the 5th International Conference on Advanced Research and Rapid Prototyping

Other

Other5th International Conference on Advanced Research in Virtual and Physical Prototyping, VR@P 2011
CountryPortugal
CityLeiria
Period9/28/1110/1/11

All Science Journal Classification (ASJC) codes

  • Artificial Intelligence
  • Computer Science Applications
  • Software

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