Spectral energy measurements of simulated microemboli of various sizes using a diffraction grating ultrasound probe

William Weiss, Sowmya G. Ballakur, Hoang Tran, Sprague William Hazard, John Blebea

Research output: Contribution to journalConference article

Abstract

This study characterizes the Doppler signal from simulated microemboli of various sizes in blood mimicking fluid using spectral energy parameters. The goal of this research is to detect microemboli as a non-invasive diagnostic tool, or intra-operatively as a surgical aid. A dual beam diffraction-grating ultrasound probe operating at 10 MHz (Model Echoflow BVM-1, EchoCath, Inc., Princeton, NJ) was used with a flow phantom. Microemboli were polystyrene microspheres in 200 to 1000 micron diameters, in concentrations of 0.1, 0.5, and 1.0 per ml. Average flow velocities were 25, 50, 75, and 100 cm/sec. The distribution of peak values of the power spectrum at 2.5 msec windows was plotted over 15 seconds. The means of the distributions corresponding to the microspheres and background fluid were averaged for the four velocity conditions. Embolic peak spectral power ranged from approximately 12 to 25 dB relative to the background. A detection method based on these measurements is currently being developed.

Original languageEnglish (US)
Pages (from-to)471-479
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5035
DOIs
StatePublished - Sep 12 2003
EventMedical Imaging 2003: Ultrasonic Imaging and Signal Processing - San Diego, CA, United States
Duration: Feb 18 2003Feb 20 2003

Fingerprint

Electric power measurement
Diffraction Grating
Microspheres
Diffraction gratings
Ultrasound
gratings (spectra)
Probe
Ultrasonics
Fluid
Fluids
probes
fluids
Polystyrenes
Phantom
Doppler
Power spectrum
Energy
Power Spectrum
Flow velocity
blood

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

@article{0f3b2b96b14a41b2ab93267f46f72d37,
title = "Spectral energy measurements of simulated microemboli of various sizes using a diffraction grating ultrasound probe",
abstract = "This study characterizes the Doppler signal from simulated microemboli of various sizes in blood mimicking fluid using spectral energy parameters. The goal of this research is to detect microemboli as a non-invasive diagnostic tool, or intra-operatively as a surgical aid. A dual beam diffraction-grating ultrasound probe operating at 10 MHz (Model Echoflow BVM-1, EchoCath, Inc., Princeton, NJ) was used with a flow phantom. Microemboli were polystyrene microspheres in 200 to 1000 micron diameters, in concentrations of 0.1, 0.5, and 1.0 per ml. Average flow velocities were 25, 50, 75, and 100 cm/sec. The distribution of peak values of the power spectrum at 2.5 msec windows was plotted over 15 seconds. The means of the distributions corresponding to the microspheres and background fluid were averaged for the four velocity conditions. Embolic peak spectral power ranged from approximately 12 to 25 dB relative to the background. A detection method based on these measurements is currently being developed.",
author = "William Weiss and Ballakur, {Sowmya G.} and Hoang Tran and Hazard, {Sprague William} and John Blebea",
year = "2003",
month = "9",
day = "12",
doi = "10.1117/12.479951",
language = "English (US)",
volume = "5035",
pages = "471--479",
journal = "Proceedings of SPIE - The International Society for Optical Engineering",
issn = "0277-786X",
publisher = "SPIE",

}

Spectral energy measurements of simulated microemboli of various sizes using a diffraction grating ultrasound probe. / Weiss, William; Ballakur, Sowmya G.; Tran, Hoang; Hazard, Sprague William; Blebea, John.

In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 5035, 12.09.2003, p. 471-479.

Research output: Contribution to journalConference article

TY - JOUR

T1 - Spectral energy measurements of simulated microemboli of various sizes using a diffraction grating ultrasound probe

AU - Weiss, William

AU - Ballakur, Sowmya G.

AU - Tran, Hoang

AU - Hazard, Sprague William

AU - Blebea, John

PY - 2003/9/12

Y1 - 2003/9/12

N2 - This study characterizes the Doppler signal from simulated microemboli of various sizes in blood mimicking fluid using spectral energy parameters. The goal of this research is to detect microemboli as a non-invasive diagnostic tool, or intra-operatively as a surgical aid. A dual beam diffraction-grating ultrasound probe operating at 10 MHz (Model Echoflow BVM-1, EchoCath, Inc., Princeton, NJ) was used with a flow phantom. Microemboli were polystyrene microspheres in 200 to 1000 micron diameters, in concentrations of 0.1, 0.5, and 1.0 per ml. Average flow velocities were 25, 50, 75, and 100 cm/sec. The distribution of peak values of the power spectrum at 2.5 msec windows was plotted over 15 seconds. The means of the distributions corresponding to the microspheres and background fluid were averaged for the four velocity conditions. Embolic peak spectral power ranged from approximately 12 to 25 dB relative to the background. A detection method based on these measurements is currently being developed.

AB - This study characterizes the Doppler signal from simulated microemboli of various sizes in blood mimicking fluid using spectral energy parameters. The goal of this research is to detect microemboli as a non-invasive diagnostic tool, or intra-operatively as a surgical aid. A dual beam diffraction-grating ultrasound probe operating at 10 MHz (Model Echoflow BVM-1, EchoCath, Inc., Princeton, NJ) was used with a flow phantom. Microemboli were polystyrene microspheres in 200 to 1000 micron diameters, in concentrations of 0.1, 0.5, and 1.0 per ml. Average flow velocities were 25, 50, 75, and 100 cm/sec. The distribution of peak values of the power spectrum at 2.5 msec windows was plotted over 15 seconds. The means of the distributions corresponding to the microspheres and background fluid were averaged for the four velocity conditions. Embolic peak spectral power ranged from approximately 12 to 25 dB relative to the background. A detection method based on these measurements is currently being developed.

UR - http://www.scopus.com/inward/record.url?scp=0041857864&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041857864&partnerID=8YFLogxK

U2 - 10.1117/12.479951

DO - 10.1117/12.479951

M3 - Conference article

AN - SCOPUS:0041857864

VL - 5035

SP - 471

EP - 479

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

SN - 0277-786X

ER -