Spontaneously acquired factor IX inhibitor in a nonhemophiliac child

Kenneth Miller, John Neely, William Krivit, J. Roger Edson

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A 2 1/2-year-old, previously healthy child developed progressive swelling of the left leg and a hematoma of the anterior chest wall associated with a falling hemoglobin concentration, as a result of a spontaneously acquired Factor IX inhibitor. Successful management of her condition, required a fourvolume exchange transfusion and immunosuppressive therapy consisting of cyclophosphamide for four days and prednisone for one month. A brief review of the literature regarding the occurrence and nature of acquired coagulation factor, inhibitors and the role of immunosuppressive therapy is also presented.

Original languageEnglish (US)
Pages (from-to)232-234
Number of pages3
JournalThe Journal of Pediatrics
Volume93
Issue number2
DOIs
StatePublished - Jan 1 1978

Fingerprint

Factor IX
Immunosuppressive Agents
Blood Coagulation Factors
Thoracic Wall
Prednisone
Hematoma
Cyclophosphamide
Leg
Hemoglobins
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Miller, Kenneth ; Neely, John ; Krivit, William ; Edson, J. Roger. / Spontaneously acquired factor IX inhibitor in a nonhemophiliac child. In: The Journal of Pediatrics. 1978 ; Vol. 93, No. 2. pp. 232-234.
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Spontaneously acquired factor IX inhibitor in a nonhemophiliac child. / Miller, Kenneth; Neely, John; Krivit, William; Edson, J. Roger.

In: The Journal of Pediatrics, Vol. 93, No. 2, 01.01.1978, p. 232-234.

Research output: Contribution to journalArticle

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