Squid-inspired tandem repeat proteins: Functional fibers and films

Abdon Pena-Francesch, Melik C. Demirel

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


Production of repetitive polypeptides that comprise one or more tandem copies of a single unit with distinct amorphous and ordered regions have been an interest for the last couple of decades. Their molecular structure provides a rich architecture that can micro-phase-separate to form periodic nanostructures (e.g., lamellar and cylindrical repeating phases) with enhanced physicochemical properties via directed or natural evolution that often exceed those of conventional synthetic polymers. Here, we review programmable design, structure, and properties of functional fibers and films from squid-inspired tandem repeat proteins, with applications in soft photonics and advanced textiles among others.

Original languageEnglish (US)
Article number69
JournalFrontiers in Chemistry
Issue numberFEB
StatePublished - 2019

All Science Journal Classification (ASJC) codes

  • Chemistry(all)


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