Stability of nicotine and cotinine unfrozen plasma

Jonathan Foulds, C. Feyerabend, J. Stapleton, M. J. Jarvis, M. A H Russell

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A study of the stability of nicotine and cotinine in unfrozen plasma was carried out in order to find out whether measurements from unfrozen samples posted to the laboratory are reliable. Plasma left at room temperature for 12 days had nicotine and cotinine concentrations which correlated highly (r > 0.99) with those in duplicate samples frozen immediately. There was no evidence of a shift in values or an increase in variability due to delayed freezing for either nicotine or cotinine. These results suggest that unfrozen plasma samples posted to the laboratory provide nicotine and cotinine measurements which are acceptably reliable for both clinical and research purposes.

Original languageEnglish (US)
Pages (from-to)41-44
Number of pages4
JournalJournal of Smoking-Related Disorders
Volume5
Issue number1
StatePublished - 1994

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Cotinine
Nicotine
Freezing
Temperature
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Foulds, J., Feyerabend, C., Stapleton, J., Jarvis, M. J., & Russell, M. A. H. (1994). Stability of nicotine and cotinine unfrozen plasma. Journal of Smoking-Related Disorders, 5(1), 41-44.
Foulds, Jonathan ; Feyerabend, C. ; Stapleton, J. ; Jarvis, M. J. ; Russell, M. A H. / Stability of nicotine and cotinine unfrozen plasma. In: Journal of Smoking-Related Disorders. 1994 ; Vol. 5, No. 1. pp. 41-44.
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Foulds, J, Feyerabend, C, Stapleton, J, Jarvis, MJ & Russell, MAH 1994, 'Stability of nicotine and cotinine unfrozen plasma', Journal of Smoking-Related Disorders, vol. 5, no. 1, pp. 41-44.

Stability of nicotine and cotinine unfrozen plasma. / Foulds, Jonathan; Feyerabend, C.; Stapleton, J.; Jarvis, M. J.; Russell, M. A H.

In: Journal of Smoking-Related Disorders, Vol. 5, No. 1, 1994, p. 41-44.

Research output: Contribution to journalArticle

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Foulds J, Feyerabend C, Stapleton J, Jarvis MJ, Russell MAH. Stability of nicotine and cotinine unfrozen plasma. Journal of Smoking-Related Disorders. 1994;5(1):41-44.