Steering acoustically propelled nanowire motors toward cells in a biologically compatible environment using magnetic fields

Suzanne Ahmed, Wei Wang, Lamar O. Mair, Robert Fraleigh, Sixing Li, Luz Angelica Castro, Mauricio Hoyos, Tony Jun Huang, Thomas E. Mallouk

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The recent discovery of fuel-free propulsion of nanomotors using acoustic energy has provided a new avenue for using nanomotors in biocompatible media. Crucial to the application of nanomotors in biosensing and biomedical applications is the ability to remotely control and steer them toward targets of interest, such as specific cells and tissues. We demonstrate in vitro magnetic steering of acoustically powered nanorod motors in a biologically compatible environment. Steering was accomplished by incorporating (40 ± 5) nm thick nickel stripes into the electrochemically grown nanowires. An external magnetic field of 40-45 mT was used to orient the motors, which were acoustically propelled along their long axes. In the absence of a magnetic field, (300 ± 30) nm diameter, (4.3 ± 0.2) μm long nanowires with (40 ± 5) nm thick magnetic stripes exhibit the same self-acoustophoretic behavior, including pattern formation into concentric nanowire circles, aligned spinning chains, and autonomous axial motion, as their non-magnetic counterparts. In a magnetic field, these wires and their paths are oriented as evidenced by their relatively linear trajectories. Coordinated motion of multiple motors and targeting of individual motors toward HeLa cells with micrometer-level precision was demonstrated.

Original languageEnglish (US)
Pages (from-to)16113-16118
Number of pages6
JournalLangmuir
Volume29
Issue number52
DOIs
StatePublished - Dec 31 2013

Fingerprint

Nanowires
nanowires
Magnetic fields
cells
magnetic fields
propulsion
Nickel
Nanorods
metal spinning
Propulsion
nanorods
micrometers
Acoustics
Trajectories
trajectories
nickel
wire
Wire
Tissue
acoustics

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

Cite this

Ahmed, Suzanne ; Wang, Wei ; Mair, Lamar O. ; Fraleigh, Robert ; Li, Sixing ; Castro, Luz Angelica ; Hoyos, Mauricio ; Huang, Tony Jun ; Mallouk, Thomas E. / Steering acoustically propelled nanowire motors toward cells in a biologically compatible environment using magnetic fields. In: Langmuir. 2013 ; Vol. 29, No. 52. pp. 16113-16118.
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Ahmed, S, Wang, W, Mair, LO, Fraleigh, R, Li, S, Castro, LA, Hoyos, M, Huang, TJ & Mallouk, TE 2013, 'Steering acoustically propelled nanowire motors toward cells in a biologically compatible environment using magnetic fields', Langmuir, vol. 29, no. 52, pp. 16113-16118. https://doi.org/10.1021/la403946j

Steering acoustically propelled nanowire motors toward cells in a biologically compatible environment using magnetic fields. / Ahmed, Suzanne; Wang, Wei; Mair, Lamar O.; Fraleigh, Robert; Li, Sixing; Castro, Luz Angelica; Hoyos, Mauricio; Huang, Tony Jun; Mallouk, Thomas E.

In: Langmuir, Vol. 29, No. 52, 31.12.2013, p. 16113-16118.

Research output: Contribution to journalArticle

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