Stereoselective total synthesis of the antitumor antibiotic (-)-bactobolin

Ravi S. Garigipati, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

The first total synthesis of the biologically active microbial metabolite bactobolin (2) has been achieved. An efficient, stereoselective route to 2 in 16 steps from previously prepared α-keto lactone 3 is outlined.

Original languageEnglish (US)
Pages (from-to)4143-4145
Number of pages3
JournalJournal of Organic Chemistry
Volume53
Issue number17
DOIs
StatePublished - Aug 1 1988

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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