Stereospecificity of thymidylate synthetase

Charles Tatum, John Vederas, Erwin Schleicher, Stephen J. Benkovic, Heinz Floss

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The stereospecific formation of the methyl group of thymidylate from uridylate and 5,10-methylene-tetrahydrofolate catalysed by thymidylate synthetase has been delineated.

Original languageEnglish (US)
Pages (from-to)218-220
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number7
DOIs
StatePublished - Dec 1 1977

All Science Journal Classification (ASJC) codes

  • Molecular Medicine

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