Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

T. M. Zydowsky, L. F. Courtney, V. Frasca, R. G. Matthews, L. D. Yuen, H. Shimizu, K. Kobayashi, S. J. Benkovic, H. G. Floss

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

The last step in the biosynthesis of methionine involves transfer of the methyl group of TV5-methyltetrahydrofolate (5-CH3-H4-folate) or its polyglutamate analogue to the sulfur of homocysteine.

Original languageEnglish (US)
Pages (from-to)3152-3153
Number of pages2
JournalJournal of the American Chemical Society
Volume108
Issue number11
DOIs
StatePublished - Jan 1 1986

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5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Polyglutamic Acid
Biosynthesis
Homocysteine
Vitamin B 12
Folic Acid
Sulfur
Methionine
Escherichia coli
5-methyltetrahydrofolate

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Zydowsky, T. M., Courtney, L. F., Frasca, V., Matthews, R. G., Yuen, L. D., Shimizu, H., ... Floss, H. G. (1986). Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B. Journal of the American Chemical Society, 108(11), 3152-3153. https://doi.org/10.1021/ja00271a081
Zydowsky, T. M. ; Courtney, L. F. ; Frasca, V. ; Matthews, R. G. ; Yuen, L. D. ; Shimizu, H. ; Kobayashi, K. ; Benkovic, S. J. ; Floss, H. G. / Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B. In: Journal of the American Chemical Society. 1986 ; Vol. 108, No. 11. pp. 3152-3153.
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Zydowsky, TM, Courtney, LF, Frasca, V, Matthews, RG, Yuen, LD, Shimizu, H, Kobayashi, K, Benkovic, SJ & Floss, HG 1986, 'Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B', Journal of the American Chemical Society, vol. 108, no. 11, pp. 3152-3153. https://doi.org/10.1021/ja00271a081

Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B. / Zydowsky, T. M.; Courtney, L. F.; Frasca, V.; Matthews, R. G.; Yuen, L. D.; Shimizu, H.; Kobayashi, K.; Benkovic, S. J.; Floss, H. G.

In: Journal of the American Chemical Society, Vol. 108, No. 11, 01.01.1986, p. 3152-3153.

Research output: Contribution to journalArticle

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T1 - Sterochemical Analysis of the Methyl Transfer Catalyzed by Cobalamin-Dependent Methionine Synthase from Escherichia coli B

AU - Zydowsky, T. M.

AU - Courtney, L. F.

AU - Frasca, V.

AU - Matthews, R. G.

AU - Yuen, L. D.

AU - Shimizu, H.

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AU - Benkovic, S. J.

AU - Floss, H. G.

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