In decerebrate cats, we found that stimulation of the mesencephalic locomotor region (MLR) attenuated the responses of neurons in the superficial laminae of the dorsal horn to thin fiber muscle afferent input. The attenuation appeared to be more effective for group III afferent input than for group IV. These findings may shed light on the interaction between central command, (i.e. the MLR) and the muscle reflex, mechanisms which both contribute to the cardiovascular responses to exercise. (C) 2000 Elsevier Science Ireland Ltd.
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