Stimulation of the MLR inhibits the discharge of dorsal horn neurons responsive to muscular contraction

Alexandr M. Degtyarenko, Marc Kaufman

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We found that electrical stimulation of the mesencephalic locomotor region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input from the triceps surae muscles. In contrast, contraction of these muscles induced by electrical stimulation of the tibial nerve activated these dorsal horn neurons. Our findings show that descending central motor commands can inhibit dorsal horn interneurons receiving input from group III afferents during exercise. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)178-182
Number of pages5
JournalBrain research
Volume880
Issue number1-2
DOIs
StatePublished - Oct 13 2000

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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