Stress, aging, and wound healing

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Stress appears to promote senescence of immune cells in a manner comparable to chronological aging. This chapter will expand on this by reviewing the human literature on stress and wound healing, and by highlighting the phenomenological and mechanistic similarities of this literature with the findings from aging research. The balance of evidence indicates that it is not aging per se, but aging in the presence of other risk factors that creates a wound healing disparity between younger and older adults. In this context, stress and depression appear to be significant risk factors for impaired healing in aging adults and, by affecting shared biological pathways, may synergistically interact with other prevalent risk factors, such as co-morbidities (e.g., diabetes), pain, malnutrition, physical inactivity, and poor self-care to impair wound healing.

Original languageEnglish (US)
Title of host publicationImmunosenescence
Subtitle of host publicationPsychosocial and Behavioral Determinants
PublisherSpringer New York
Pages63-79
Number of pages17
ISBN (Electronic)9781461447764
ISBN (Print)1461447755, 9781461447757
DOIs
StatePublished - May 1 2012

Fingerprint

Wound Healing
Cell Aging
Self Care
Malnutrition
Young Adult
Depression
Morbidity
Pain
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Engeland, C. G. (2012). Stress, aging, and wound healing. In Immunosenescence: Psychosocial and Behavioral Determinants (pp. 63-79). Springer New York. https://doi.org/10.1007/978-1-4614-4776-4_5
Engeland, Christopher Gerald. / Stress, aging, and wound healing. Immunosenescence: Psychosocial and Behavioral Determinants. Springer New York, 2012. pp. 63-79
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Engeland, CG 2012, Stress, aging, and wound healing. in Immunosenescence: Psychosocial and Behavioral Determinants. Springer New York, pp. 63-79. https://doi.org/10.1007/978-1-4614-4776-4_5

Stress, aging, and wound healing. / Engeland, Christopher Gerald.

Immunosenescence: Psychosocial and Behavioral Determinants. Springer New York, 2012. p. 63-79.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Engeland CG. Stress, aging, and wound healing. In Immunosenescence: Psychosocial and Behavioral Determinants. Springer New York. 2012. p. 63-79 https://doi.org/10.1007/978-1-4614-4776-4_5