Strong-field ionization of sputtered molecules for biomolecular imaging

D. Willingham, A. Kucher, Nicholas Winograd

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Photoionization of molecules sputtered from molecular thin films has been achieved using high field 125 fs pulses in the mid-IR spectral range. Using several model systems, we show that it is possible to significantly reduce molecular fragmentation induced by the laser field by increasing the photoionization wavelength. By examining the photoionization spectra as a function of wavelength, it is apparent that the photoionization mechanism is changing from a non-adiabatic multi-electron excitation process to a process that involves tunnel ionization. The results of these observations are discussed in terms of their significance for bioimaging with focused ion beams and mass-spectrometry.

Original languageEnglish (US)
Pages (from-to)264-269
Number of pages6
JournalChemical Physics Letters
Volume468
Issue number4-6
DOIs
StatePublished - Jan 22 2009

Fingerprint

Photoionization
Ionization
photoionization
Imaging techniques
ionization
Molecules
molecules
Wavelength
Focused ion beams
wavelengths
Mass spectrometry
tunnels
Tunnels
fragmentation
mass spectroscopy
ion beams
Thin films
Electrons
Lasers
thin films

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

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Strong-field ionization of sputtered molecules for biomolecular imaging. / Willingham, D.; Kucher, A.; Winograd, Nicholas.

In: Chemical Physics Letters, Vol. 468, No. 4-6, 22.01.2009, p. 264-269.

Research output: Contribution to journalArticle

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