Structure and activity of glycosylphosphatidylinositol anchors of Plasmodium falciparum

D. Channe Gowda

doi:10.1016/S1286-4579(02)01619-2

Structure and activity of glycosylphosphatidylinositol anchors of Plasmodium falciparum

D. Channe Gowda

Department of Biochemistry and Molecular Biology

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

The glycosylphosphatidylinositol (GPI) anchors of Plasmodium falciparum are thought to be etiologic agents of malaria based on their ability to induce proinflammatory cytokine production by macrophages and cause symptoms that resemble severe malaria illness in animals. This review summarizes the published information on the structures of P. falciparum GPIs, structure-activity relationship, and anti-GPI antibodies in the host.

Original language	English (US)
Pages (from-to)	983-990
Number of pages	8
Journal	Microbes and Infection
Volume	4
Issue number	9
DOIs	https://doi.org/10.1016/S1286-4579(02)01619-2
State	Published - 2002

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S1286-4579(02)01619-2

Cite this

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abstract = "The glycosylphosphatidylinositol (GPI) anchors of Plasmodium falciparum are thought to be etiologic agents of malaria based on their ability to induce proinflammatory cytokine production by macrophages and cause symptoms that resemble severe malaria illness in animals. This review summarizes the published information on the structures of P. falciparum GPIs, structure-activity relationship, and anti-GPI antibodies in the host.",

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AB - The glycosylphosphatidylinositol (GPI) anchors of Plasmodium falciparum are thought to be etiologic agents of malaria based on their ability to induce proinflammatory cytokine production by macrophages and cause symptoms that resemble severe malaria illness in animals. This review summarizes the published information on the structures of P. falciparum GPIs, structure-activity relationship, and anti-GPI antibodies in the host.

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Structure and activity of glycosylphosphatidylinositol anchors of Plasmodium falciparum

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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