Studies of the base composition of transfer rna and the specificity of transfer rna methylases of hamster liver

Ann Jackson, Anthony E. Pegg

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

1. 1. In contrast to previous reports, examination of the base composition of tRNA preparations isolated from hamster liver showed a minor base composition similar to that of rat liver tRNA. 2. 2. tRNA methylases isolated from hamster liver tRNA were also similar to those present in rat liver extracts. 3. 3. The same methylated nucleosides were formed when unfractionated undermethylated tRNA from E. coli was used as a substrate for methylation by enzymes from either of these species. 4. 4. The same sites within the transfer RNA sequence were attacked when purified tRNA species from E. coli and yeast were used as substrates.

Original languageEnglish (US)
Pages (from-to)35-42
Number of pages8
JournalInternational Journal of Biochemistry
Volume6
Issue number1
DOIs
StatePublished - Jan 1975

All Science Journal Classification (ASJC) codes

  • Biochemistry

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