Studies on total synthesis of the cylindricine/fasicularin/lepadiformine family of tricyclic marine alkaloids

Steven M. Weinreb

Research output: Contribution to journalReview articlepeer-review

109 Scopus citations

Abstract

This review covers the isolation of a family of structurally related tricyclic alkaloids. Topics discussed include the isolation and structure determination, biological activity, synthetic approaches to the cylindricines, synthesis of fasicularin, and synthesis and structure determination of lepadiformine. Furthermore, the Hsung synthesis of (-)-cylindricine C and the Renaud synthesis of (±)-lepadiformine are also considered.

Original languageEnglish (US)
Pages (from-to)2531-2549
Number of pages19
JournalChemical Reviews
Volume106
Issue number6
DOIs
StatePublished - Jun 2006

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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