Study of thinly sectioned melanoma skin tissues with mechanical scanning acoustic reflection microscopy

B. R. Tittmann, C. Miyaska, Y. Tian, E. Maeva, D. Shum

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The contents of the present report are focused on characterizing a thinly sectioned skin tissue with a mechanical scanning acoustic reflection microscope (tone-burst-wave mode) and describes the quantitative data acquisition technique with V(z) analysis. The reflectance function for the tissue located on a substrate was theoretically determined, and fitted into the mathematical model of the V(z) curve. The V(z) curves with frequency at 200 MHz for thinly sectioned normal and abnormal tissues located on soda-lime glasses were theoretically and experimentally formed. Their leaky surface acoustic wave velocities were obtained by the experimentally formed V(z) curves through FFT analyses. Finally, a computer simulation with a parameter-fitting technique (i.e., matching the distances of the periods of the theoretical and experimental V(z) curves by inputting different longitudinal wave velocities and densities of the tissue) was implemented to obtain the longitudinal wave velocities and densities of the tissues. The obtained longitudinal wave velocity may be used to simulate contrast analysis.

Original languageEnglish (US)
Title of host publicationHealth Monitoring of Structural and Biological Systems 2011
DOIs
StatePublished - 2011
EventHealth Monitoring of Structural and Biological Systems 2011 - San Diego, CA, United States
Duration: Mar 7 2011Mar 10 2011

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7984
ISSN (Print)0277-786X

Other

OtherHealth Monitoring of Structural and Biological Systems 2011
CountryUnited States
CitySan Diego, CA
Period3/7/113/10/11

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Study of thinly sectioned melanoma skin tissues with mechanical scanning acoustic reflection microscopy'. Together they form a unique fingerprint.

Cite this