Submicrometer metallic barcodes

S. R. Nicewarner-Peña, R. G. Freeman, B. D. Reiss, L. He, D. J. Peña, I. D. Walton, R. Cromer, C. D. Keating, M. J. Natan

Research output: Contribution to journalArticle

1203 Scopus citations

Abstract

We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.

Original languageEnglish (US)
Pages (from-to)137-141
Number of pages5
JournalScience
Volume294
Issue number5540
DOIs
StatePublished - Oct 5 2001

All Science Journal Classification (ASJC) codes

  • General

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    Nicewarner-Peña, S. R., Freeman, R. G., Reiss, B. D., He, L., Peña, D. J., Walton, I. D., Cromer, R., Keating, C. D., & Natan, M. J. (2001). Submicrometer metallic barcodes. Science, 294(5540), 137-141. https://doi.org/10.1126/science.294.5540.137