Successful liver transplant complicated by severe portopulmonary hypertension after an initial aborted attempt: Case report and review of treatment options

Research output: Contribution to journalReview article

Abstract

Good right ventricular function and responsiveness to vasodilator therapy are the most important prerequisites for successful liver transplant in patients with portopulmonary hypertension. A patient with portopulmonary hypertension and good right ventricular function presented for deceased-donor liver transplant. Pulmonary arterial pressure was controlled with epoprostenol and sildenafil preoperatively. After anesthesia induction, pulmonary arterial pressure increased significantly and the procedure was aborted. Additional medical treatment included aggressive vasodilator therapy and the transplant was successfully performed 1 month later. During the procedure, elevations in pulmonary arterial pressure responded to a combination of inhaled nitric oxide, intravenous milrinone and nitroglycerin, and optimization of mechanical ventilation.

Original languageEnglish (US)
Pages (from-to)361-365
Number of pages5
JournalExperimental and Clinical Transplantation
Volume15
Issue number3
DOIs
StatePublished - Jun 2017

All Science Journal Classification (ASJC) codes

  • Transplantation

Fingerprint Dive into the research topics of 'Successful liver transplant complicated by severe portopulmonary hypertension after an initial aborted attempt: Case report and review of treatment options'. Together they form a unique fingerprint.

  • Cite this