Successful pregnancy resulting from cryopreserved pronuclear and cleaved embryos thawed and cultured to blastocysts, refrozen and transferred: A case report

Stephanie J. Estes, Donna C. Laky, Linda M. Hoover, Scott E. Smith, Jay S. Schinfeld, Stephen G. Somkuti

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

BACKGROUND: Twice-frozen, thawed embryos may have utilization in in vitro fertilization (IVF) cycles. CASE: A 37-year-old woman with endometriosis and infertility returned five years after a fresh IVF cycle. Seven cryopreserved embryos (2 pronuclear [pn] and cleaved) were thawed, and five developed to the blastocyst stage. One blastocyst was transferred, and the remaining four were recryopreserved. This transfer did not result in pregnancy. The remaining four blastocysts were thawed, and two were transferred resulting in a live, singleton delivery. CONCLUSION: Pregnancy can result from cryopreserved 2-pn and cleaved embryos cultured to blastocysts, refrozen and then transferred at the blastocyst stage.

Original languageEnglish (US)
Pages (from-to)46-48
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume48
Issue number1
StatePublished - Jan 1 2003

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

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