Sum frequency generation studies on bioadhesion: Elucidating the molecular structure of proteins at interfaces

Stephanie Valerie Le Clair, Khoi Nguyen, Zhan Chen

Research output: Contribution to journalReview article

16 Scopus citations


The study of bioadhesion is significant to applications in a variety of scientific fields. Techniques that are surface-sensitive need to be utilized to examine these kinds of systems because bioadhesion occurs at the interface between two surfaces. Recently, sum frequency generation (SFG) has been applied to investigate different bioadhesive processes because of its intrinsic surface specificity, excellent sensitivity, and its ability to perform experiments in situ. SFG studies on the bioadhesion of fibrinogen, Factor XII, and mefp-3 on various surfaces will be discussed in this review.

Original languageEnglish (US)
Pages (from-to)484-511
Number of pages28
JournalJournal of Adhesion
Issue number8
StatePublished - Sep 3 2009


All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Mechanics of Materials
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Materials Chemistry

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