Surface biofunctionalization of nanostructured GeSbSe chalcogenide glass thin films

R. J. Martín-Palma, M. C. Demirel, H. Wang, C. G. Pantano

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Thin nanostructured chalcogenide films were grown using the oblique angle deposition (OAD) technique and subsequently polymerized with thin poly(amino-p-xylylene) (PPX) films. Our objective was twofold, i.e., to use deposited polymeric thin films to allow the attachment of biomolecules to chalcogenide glass thin films, and at the same time, to increase surface area by OAD to enhance surface functionality. The effectiveness of this approach was evaluated by Fourier transform infrared spectroscopy (FTIR), together with a combination of fluorescent protein immobilization and confocal microscopy characterization. It is shown that the presence of amine groups on the surface of the polymer coated chalcogenide thin films yield a notable increment of surface coverage with proteins at large evaporation oblique angles which is expected to enhance detection performance of the film in biosensor applications.

Original languageEnglish (US)
Pages (from-to)208-212
Number of pages5
JournalJournal of Non-Crystalline Solids
Volume355
Issue number3
DOIs
StatePublished - Feb 1 2009

Fingerprint

Glass
Thin films
glass
thin films
proteins
Proteins
Confocal microscopy
Biomolecules
immobilization
bioinstrumentation
Polymer films
Biosensors
Amines
attachment
Fourier transform infrared spectroscopy
amines
Polymers
Evaporation
infrared spectroscopy
evaporation

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

Martín-Palma, R. J. ; Demirel, M. C. ; Wang, H. ; Pantano, C. G. / Surface biofunctionalization of nanostructured GeSbSe chalcogenide glass thin films. In: Journal of Non-Crystalline Solids. 2009 ; Vol. 355, No. 3. pp. 208-212.
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Surface biofunctionalization of nanostructured GeSbSe chalcogenide glass thin films. / Martín-Palma, R. J.; Demirel, M. C.; Wang, H.; Pantano, C. G.

In: Journal of Non-Crystalline Solids, Vol. 355, No. 3, 01.02.2009, p. 208-212.

Research output: Contribution to journalArticle

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AB - Thin nanostructured chalcogenide films were grown using the oblique angle deposition (OAD) technique and subsequently polymerized with thin poly(amino-p-xylylene) (PPX) films. Our objective was twofold, i.e., to use deposited polymeric thin films to allow the attachment of biomolecules to chalcogenide glass thin films, and at the same time, to increase surface area by OAD to enhance surface functionality. The effectiveness of this approach was evaluated by Fourier transform infrared spectroscopy (FTIR), together with a combination of fluorescent protein immobilization and confocal microscopy characterization. It is shown that the presence of amine groups on the surface of the polymer coated chalcogenide thin films yield a notable increment of surface coverage with proteins at large evaporation oblique angles which is expected to enhance detection performance of the film in biosensor applications.

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