Surgical management of early-stage non-small cell lung carcinoma and the present and future roles of adjuvant therapy: A review for the radiation oncologist

Laura Medford-Davis, Malcom Decamp, Abram Recht, John Flickinger, Chandra Belani, John Varlotto

Research output: Contribution to journalReview article

9 Scopus citations

Abstract

We review the evidence for optimal surgical management and adjuvant therapy for patients with stages I and II non-small cell lung cancer (NSCLC) along with factors associated with increased risks of recurrence. Based on the current evidence, we recommend optimal use of mediastinal lymph node dissection, adjuvant chemotherapy, and post-operative radiation therapy, and make suggestions for areas to explore in future prospective randomized clinical trials.

Original languageEnglish (US)
Pages (from-to)1048-1057
Number of pages10
JournalInternational Journal of Radiation Oncology Biology Physics
Volume84
Issue number5
DOIs
Publication statusPublished - Dec 1 2012

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All Science Journal Classification (ASJC) codes

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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