Surgical removal of submacular choroidal neovascularization: A clinicopathologic study and factors influencing visual outcomes

R. P. Corey, I. U. Scott, Jr Flynn, Jr Rosa, T. G. Murray

Research output: Contribution to journalArticle

5 Scopus citations


BACKGROUND AND OBJECTIVE: Clinical and histopathologic characteristics of submacular choroidal neovascular membranes (CNV) are investigated and features predictive of postoperative complications or poorer visual outcome following CNV removal are identified. MATERIALS AND METHODS: Records of patients who underwent submacular CNV removal at Bascom Palmer Eye Institute between 1991 and 1998 are reviewed. RESULTS: At 6 months postoperatively, vision was stable or improved in 19/26 (73%) eyes, with 15/26 (58%) having 20/200 to 20/400 vision. Postoperative retinal detachment occurred more commonly in age-related macular degeneration eyes (AMD) (P <0.05), and CNV recurrence occurred most frequently in presumed ocular histoplasmosis (POHS) eyes (P <0.05). The one eye with an extrafoveal CNV in-growth site had the largest improvement in vision postoperatively. Choroid in the specimen was associated with worse postoperative vision (P = 0.05). CONCLUSION: Submacular CNV removal achieves visual stabilization at the 20/200 to 20/400 level in most eyes. Potential risk factors for postoperative complications or poorer visual outcome include the underlying disease process, subfoveal in-growth site of CNV, and presence of choroid in the specimen.

Original languageEnglish (US)
Pages (from-to)406-418
Number of pages13
JournalOphthalmic Surgery and Lasers
Issue number5
Publication statusPublished - Sep 26 2001


All Science Journal Classification (ASJC) codes

  • Ophthalmology

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