Surgical resection for hepatocellular carcinoma

Amanda Cooper, Thomas A. Aloia

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The incidence of hepatocellular carcinoma (HCC) is growing in the United States due to increasing rates of cirrhosis from viral hepatitis, alcohol, and fatty liver disease. The elevated incidence, along with the associated high mortality rate for patients with this diagnosis, highlights the importance of an understanding of the optimal management of HCC. Surgical resection and liver transplantation offer the only options for long-term cure. However, without careful patient selection, meticulous intraoperative technique and perioperative management, liver resection in patients with underlying cirrhosis is associated with a significant risk of postoperative morbidity and/or mortality. This article will describe key considerations in patient selection and recent improvements in surgical technique and peri-operative management that have increased the safety of liver resection in patients with HCC, particularly those with underlying cirrhosis.

Original languageEnglish (US)
Pages (from-to)450-459
Number of pages10
JournalTranslational Cancer Research
Issue number6
StatePublished - Dec 1 2013

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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