Surgical treatment of colorectal liver metastases

Amanda B. Cooper, Steven A. Curley

Research output: Contribution to journalReview article

Abstract

The incidence of colorectal cancer is rising in China. Since nearly 50% of these patients will ultimately develop liver metastases, an understanding of the surgical management of hepatic metastases is important. Surgical strategies for the management of liver metastases have evolved in recent years and now include adjunctive procedures such as portal vein embolization and radiofrequency ablation, which can help increase the number of patients eligible for potentially curative surgical management. In addition, innovations in treatment sequencing, including the use of peri-operative chemotherapy and the liver-first approach to the management of synchronous liver metastases have helped improve outcomes in these patients. Along with such changes in surgical management come new risks, such as chemotherapy-induced liver damage, with which the surgeon must be prepared to contend.

Original languageEnglish (US)
JournalChinese clinical oncology
Volume2
Issue number2
DOIs
StatePublished - Jan 1 2013

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Neoplasm Metastasis
Liver
Therapeutics
Drug Therapy
Portal Vein
Colorectal Neoplasms
China
Incidence

All Science Journal Classification (ASJC) codes

  • Oncology

Cite this

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title = "Surgical treatment of colorectal liver metastases",
abstract = "The incidence of colorectal cancer is rising in China. Since nearly 50{\%} of these patients will ultimately develop liver metastases, an understanding of the surgical management of hepatic metastases is important. Surgical strategies for the management of liver metastases have evolved in recent years and now include adjunctive procedures such as portal vein embolization and radiofrequency ablation, which can help increase the number of patients eligible for potentially curative surgical management. In addition, innovations in treatment sequencing, including the use of peri-operative chemotherapy and the liver-first approach to the management of synchronous liver metastases have helped improve outcomes in these patients. Along with such changes in surgical management come new risks, such as chemotherapy-induced liver damage, with which the surgeon must be prepared to contend.",
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Surgical treatment of colorectal liver metastases. / Cooper, Amanda B.; Curley, Steven A.

In: Chinese clinical oncology, Vol. 2, No. 2, 01.01.2013.

Research output: Contribution to journalReview article

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T1 - Surgical treatment of colorectal liver metastases

AU - Cooper, Amanda B.

AU - Curley, Steven A.

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Y1 - 2013/1/1

N2 - The incidence of colorectal cancer is rising in China. Since nearly 50% of these patients will ultimately develop liver metastases, an understanding of the surgical management of hepatic metastases is important. Surgical strategies for the management of liver metastases have evolved in recent years and now include adjunctive procedures such as portal vein embolization and radiofrequency ablation, which can help increase the number of patients eligible for potentially curative surgical management. In addition, innovations in treatment sequencing, including the use of peri-operative chemotherapy and the liver-first approach to the management of synchronous liver metastases have helped improve outcomes in these patients. Along with such changes in surgical management come new risks, such as chemotherapy-induced liver damage, with which the surgeon must be prepared to contend.

AB - The incidence of colorectal cancer is rising in China. Since nearly 50% of these patients will ultimately develop liver metastases, an understanding of the surgical management of hepatic metastases is important. Surgical strategies for the management of liver metastases have evolved in recent years and now include adjunctive procedures such as portal vein embolization and radiofrequency ablation, which can help increase the number of patients eligible for potentially curative surgical management. In addition, innovations in treatment sequencing, including the use of peri-operative chemotherapy and the liver-first approach to the management of synchronous liver metastases have helped improve outcomes in these patients. Along with such changes in surgical management come new risks, such as chemotherapy-induced liver damage, with which the surgeon must be prepared to contend.

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