Suscettibilità a diossina in soggetti cloracneici della popolazione di Seveso

Translated title of the contribution: Susceptibility to dioxin among individuals from Seveso suffering from cloracne

M. Bonzini, A. Baccarelli, A. Pesatori, D. Consonni, Donald George Jr Patterson, M. Rubagotti, N. E. Caporaso, P. A. Bertazzi, M. T. Landi

Research output: Contribution to journalArticlepeer-review


Approximately 20 years after the Seveso accident, we designed a case-control study on 101 subjects who developed chloracne after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and 211 controls from the same area, to establish the dose-exposure relation and to identify dioxin susceptibility factors. Subjects with elevated plasma TCDD levels (>10 pg/g fat) showed an almost 4 times higher risk of developing chloracne. Chloracne risk was higher in subjects with high TCDD plasma levels, young people (≤8 years) and/or those with fair hair. The health status of chloracne cases twenty years after the accident was not different from that of control subjects.

Translated title of the contributionSusceptibility to dioxin among individuals from Seveso suffering from cloracne
Original languageItalian
Pages (from-to)27-29
Number of pages3
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Issue number4 SUPPL.
StatePublished - Nov 26 2004

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health


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