Synthesis of a chiral binaphthyldisulfide: A potentially useful reagent for catalytic asymmetric synthesis

Ken S. Feldman, Robert E. Ruckle, Susan M. Ensel, Paul H. Weinreb

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Diels Alder cycloaddition/oxygen-atom-extrusion provides the means to unite two naphthylene fragments and affords a highly functionalized, racemic binaphthyl iodide. Resolution of a derived thiol then furnishes, after appropriate manipulation, enantiomerically pure binaphthyldisulfide precatalysts.

Original languageEnglish (US)
Pages (from-to)7101-7102
Number of pages2
JournalTetrahedron Letters
Volume33
Issue number47
DOIs
StatePublished - Nov 17 1992

Fingerprint

Cycloaddition
Cycloaddition Reaction
Iodides
Sulfhydryl Compounds
Extrusion
Oxygen
Atoms

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Feldman, Ken S. ; Ruckle, Robert E. ; Ensel, Susan M. ; Weinreb, Paul H. / Synthesis of a chiral binaphthyldisulfide : A potentially useful reagent for catalytic asymmetric synthesis. In: Tetrahedron Letters. 1992 ; Vol. 33, No. 47. pp. 7101-7102.
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Synthesis of a chiral binaphthyldisulfide : A potentially useful reagent for catalytic asymmetric synthesis. / Feldman, Ken S.; Ruckle, Robert E.; Ensel, Susan M.; Weinreb, Paul H.

In: Tetrahedron Letters, Vol. 33, No. 47, 17.11.1992, p. 7101-7102.

Research output: Contribution to journalArticle

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AU - Weinreb, Paul H.

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