Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid

Thomas A. Lessen, Donald M. Demko, Steven M. Weinreb

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

A key intramolecular N-acyliminium ion/silylenol ether cyclization of 17, derived from L-glutamic acid, has been used to construct the bridged bicyclic quinocarcin intermediate 3.

Original languageEnglish (US)
Pages (from-to)2105-2108
Number of pages4
JournalTetrahedron Letters
Volume31
Issue number15
DOIs
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of an advanced quinocarcin intermediate from 1-glutamic acid'. Together they form a unique fingerprint.

  • Cite this