Synthesis of methyl 3-deoxy-3-methylaminoarabinopyranoside, a component of some aminoglycoside antibiotics

Stacy W. Remiszewski, Terry R. Stouch, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Amino sugar 1 has been synthesized in racemic form as a mixture of anomers from sorbic aldehyde. An intramolecular N-sulfinyl dienophile Diels-Alder strategy was used to stereospecifically generate the chiral centers of pentose 1.

Original languageEnglish (US)
Pages (from-to)1173-1178
Number of pages6
JournalTetrahedron
Volume41
Issue number7
DOIs
StatePublished - 1985

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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