Synthesis of novel cyclic sulfone dihydropyridines facilitated by a selective ethyl diazoacetate ring expansion

John H. Dodd, Charles F. Schwender, Yolanda Gray‐Nunez

Research output: Contribution to journalArticle

14 Scopus citations


A series of novel cyclic sulfone dihydropyridines with five to nine membered rings have been synthesized. Anomalous intermediates isolated from the Hantzch condensation were found to vary depending on the sulfone ring size and aromatic substitution. Tin tetrachloride has been shown to be a superior Lewis acid catalyst for ethyl diazoacetate ring expansion of the requesite β‐keto cyclic sulfone precursors.

Original languageEnglish (US)
Pages (from-to)1453-1456
Number of pages4
JournalJournal of Heterocyclic Chemistry
Issue number5
Publication statusPublished - Jan 1 1990


All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this