Synthesis of polychlorinated biphenylenes (PCBPs): Structural characterization of 2,3,6,7-TCBP and analysis for PCBPs in human adipose tissue by negative-ion chemical ionization (NCI) mass spectrometry

E. R. Barnhart, Donald George Jr Patterson, D. L. Ashley, C. C. Alley, J. A.H. MacBride

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A tetrachlorobiphenylene was isolated from a SO2Cl2-biphenylene reaction mixture by reversed-phase liquid chromatography. The structural assignment of 2,3,6,7-tetrachloro-biphenylene is based on data from the synthesis route, gas chromatography/mass spectrometry, and nuclear magnetic resonance longitudinal relaxation studies. The UV photolysis of octachlorobiphenylene (OCBP) produced a mixture of tetra through octachlorobiphenylenes which provided a standard to assess the retention times of biphenylenes relative to PCDDs and PCDFs. The recoveries of the biphenylenes through the adipose tissue cleanup procedures developed for PCDDs and PCDFs ranged from 62-92%. Composite extracts from control and exposed groups were analyzed by NCI mass spectrometry and no peaks characteristic of biphenylenes were found.

Original languageEnglish (US)
Pages (from-to)2057-2062
Number of pages6
JournalChemosphere
Volume16
Issue number8-9
DOIs
StatePublished - Jan 1 1987

Fingerprint

PCDF
PCDD
Ionization
Mass spectrometry
Adipose Tissue
Mass Spectrometry
ionization
Negative ions
mass spectrometry
Ions
Tissue
ion
Photolysis
Liquid chromatography
Reverse-Phase Chromatography
photolysis
cleanup
Gas chromatography
Gas Chromatography-Mass Spectrometry
Longitudinal Studies

All Science Journal Classification (ASJC) codes

  • Environmental Engineering
  • Environmental Chemistry
  • Chemistry(all)
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Barnhart, E. R. ; Patterson, Donald George Jr ; Ashley, D. L. ; Alley, C. C. ; MacBride, J. A.H. / Synthesis of polychlorinated biphenylenes (PCBPs) : Structural characterization of 2,3,6,7-TCBP and analysis for PCBPs in human adipose tissue by negative-ion chemical ionization (NCI) mass spectrometry. In: Chemosphere. 1987 ; Vol. 16, No. 8-9. pp. 2057-2062.
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abstract = "A tetrachlorobiphenylene was isolated from a SO2Cl2-biphenylene reaction mixture by reversed-phase liquid chromatography. The structural assignment of 2,3,6,7-tetrachloro-biphenylene is based on data from the synthesis route, gas chromatography/mass spectrometry, and nuclear magnetic resonance longitudinal relaxation studies. The UV photolysis of octachlorobiphenylene (OCBP) produced a mixture of tetra through octachlorobiphenylenes which provided a standard to assess the retention times of biphenylenes relative to PCDDs and PCDFs. The recoveries of the biphenylenes through the adipose tissue cleanup procedures developed for PCDDs and PCDFs ranged from 62-92{\%}. Composite extracts from control and exposed groups were analyzed by NCI mass spectrometry and no peaks characteristic of biphenylenes were found.",
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Synthesis of polychlorinated biphenylenes (PCBPs) : Structural characterization of 2,3,6,7-TCBP and analysis for PCBPs in human adipose tissue by negative-ion chemical ionization (NCI) mass spectrometry. / Barnhart, E. R.; Patterson, Donald George Jr; Ashley, D. L.; Alley, C. C.; MacBride, J. A.H.

In: Chemosphere, Vol. 16, No. 8-9, 01.01.1987, p. 2057-2062.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis of polychlorinated biphenylenes (PCBPs)

T2 - Structural characterization of 2,3,6,7-TCBP and analysis for PCBPs in human adipose tissue by negative-ion chemical ionization (NCI) mass spectrometry

AU - Barnhart, E. R.

AU - Patterson, Donald George Jr

AU - Ashley, D. L.

AU - Alley, C. C.

AU - MacBride, J. A.H.

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