Synthesis of Sugar-Substituted Cyclic and Polymeric Phosphazenes and Their Oxidation, Reduction, and Acetylation Reactions

Harry R. Allcock, Angelo G. Scopelianos

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Sugar residues have been linked to cyclic and high-polymeric phosphazenes. Selective blocking of the 1,2- and 5,6-hydroxyl groups of α-D-glucose by acetone allowed linkage to the phosphazene via the remaining hydroxyl unit. Hydrolysis of the blocked, sugar-substituted phosphazenes brought about deprotection. The deprotected derivatives were then modified chemically by oxidation, reduction, and acetylation. The resultant high polymers are the first members of a new class of hydrophilic or water-soluble macromolecules. Their properties and structural characterization are discussed.

Original languageEnglish (US)
Pages (from-to)715-719
Number of pages5
JournalMacromolecules
Volume16
Issue number5
DOIs
StatePublished - Jan 1 1983

Fingerprint

Acetylation
Sugars
Hydroxyl Radical
Acetone
Macromolecules
Glucose
Hydrolysis
Polymers
Derivatives
Water
Oxidation-Reduction

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

Cite this

@article{cc4dc28862b7413d9da3ea3a5086c4fd,
title = "Synthesis of Sugar-Substituted Cyclic and Polymeric Phosphazenes and Their Oxidation, Reduction, and Acetylation Reactions",
abstract = "Sugar residues have been linked to cyclic and high-polymeric phosphazenes. Selective blocking of the 1,2- and 5,6-hydroxyl groups of α-D-glucose by acetone allowed linkage to the phosphazene via the remaining hydroxyl unit. Hydrolysis of the blocked, sugar-substituted phosphazenes brought about deprotection. The deprotected derivatives were then modified chemically by oxidation, reduction, and acetylation. The resultant high polymers are the first members of a new class of hydrophilic or water-soluble macromolecules. Their properties and structural characterization are discussed.",
author = "Allcock, {Harry R.} and Scopelianos, {Angelo G.}",
year = "1983",
month = "1",
day = "1",
doi = "10.1021/ma00239a001",
language = "English (US)",
volume = "16",
pages = "715--719",
journal = "Macromolecules",
issn = "0024-9297",
publisher = "American Chemical Society",
number = "5",

}

Synthesis of Sugar-Substituted Cyclic and Polymeric Phosphazenes and Their Oxidation, Reduction, and Acetylation Reactions. / Allcock, Harry R.; Scopelianos, Angelo G.

In: Macromolecules, Vol. 16, No. 5, 01.01.1983, p. 715-719.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis of Sugar-Substituted Cyclic and Polymeric Phosphazenes and Their Oxidation, Reduction, and Acetylation Reactions

AU - Allcock, Harry R.

AU - Scopelianos, Angelo G.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - Sugar residues have been linked to cyclic and high-polymeric phosphazenes. Selective blocking of the 1,2- and 5,6-hydroxyl groups of α-D-glucose by acetone allowed linkage to the phosphazene via the remaining hydroxyl unit. Hydrolysis of the blocked, sugar-substituted phosphazenes brought about deprotection. The deprotected derivatives were then modified chemically by oxidation, reduction, and acetylation. The resultant high polymers are the first members of a new class of hydrophilic or water-soluble macromolecules. Their properties and structural characterization are discussed.

AB - Sugar residues have been linked to cyclic and high-polymeric phosphazenes. Selective blocking of the 1,2- and 5,6-hydroxyl groups of α-D-glucose by acetone allowed linkage to the phosphazene via the remaining hydroxyl unit. Hydrolysis of the blocked, sugar-substituted phosphazenes brought about deprotection. The deprotected derivatives were then modified chemically by oxidation, reduction, and acetylation. The resultant high polymers are the first members of a new class of hydrophilic or water-soluble macromolecules. Their properties and structural characterization are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0008447819&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0008447819&partnerID=8YFLogxK

U2 - 10.1021/ma00239a001

DO - 10.1021/ma00239a001

M3 - Article

AN - SCOPUS:0008447819

VL - 16

SP - 715

EP - 719

JO - Macromolecules

JF - Macromolecules

SN - 0024-9297

IS - 5

ER -