Synthesis of the tetracyclic skeleton of the lycopodium alkaloid lycopladine H via a pivotal double hydroformylation/intramolecular reductive amination sequence

Pradeep S. Chauhan, Joshua R. Sacher, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

A synthesis of the complete tetracyclic framework of the structurally unique Lycopodium alkaloid lycopladine H has been accomplished using a strategy involving a double alkene hydroformylation/intramolecular reductive amination to form the azocane and spiro-piperidine moieties of the natural product.

Original languageEnglish (US)
Pages (from-to)806-808
Number of pages3
JournalOrganic Letters
Volume17
Issue number4
DOIs
StatePublished - Feb 20 2015

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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